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1.

PCSK9 Inhibitors.

Natarajan, Pradeep; Kathiresan, Sekar.

Cell ; 165(5): 1037, 2016 May 19.

Artículo en Inglés | MEDLINE | ID: mdl-27203103

2.

Genetic variation across and within individuals.

Yu, Zhi; Coorens, Tim H H; Uddin, Md Mesbah; Ardlie, Kristin G; Lennon, Niall; Natarajan, Pradeep.

Nat Rev Genet ; 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38548833

3.

Clonal haematopoiesis and risk of chronic liver disease.

Wong, Waihay J; Emdin, Connor; Bick, Alexander G; Zekavat, Seyedeh M; Niroula, Abhishek; Pirruccello, James P; Dichtel, Laura; Griffin, Gabriel; Uddin, Md Mesbah; Gibson, Christopher J; Kovalcik, Veronica; Lin, Amy E; McConkey, Marie E; Vromman, Amelie; Sellar, Rob S; Kim, Peter G; Agrawal, Mridul; Weinstock, Joshua; Long, Michelle T; Yu, Bing; Banerjee, Rajarshi; Nicholls, Rowan C; Dennis, Andrea; Kelly, Matt; Loh, Po-Ru; McCarroll, Steve; Boerwinkle, Eric; Vasan, Ramachandran S; Jaiswal, Siddhartha; Johnson, Andrew D; Chung, Raymond T; Corey, Kathleen; Levy, Daniel; Ballantyne, Christie; Ebert, Benjamin L; Natarajan, Pradeep.

Nature ; 616(7958): 747-754, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-37046084

4.

The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care.

Vassy, Jason L; Brunette, Charles A; Lebo, Matthew S; MacIsaac, Katharine; Yi, Thomas; Danowski, Morgan E; Alexander, Nicholas V J; Cardellino, Mark P; Christensen, Kurt D; Gala, Manish; Green, Robert C; Harris, Elizabeth; Jones, Natalie E; Kerman, Benjamin J; Kraft, Peter; Kulkarni, Preetika; Lewis, Anna C F; Lubitz, Steven A; Natarajan, Pradeep; Antwi, Ashley A.

Am J Hum Genet ; 110(11): 1841-1852, 2023 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-37922883

5.

Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.

Liu, Wenli; Pircher, Joachim; Schuermans, Art; Ul Ain, Qurrat; Zhang, Zhe; Honigberg, Michael C; Yalcinkaya, Mustafa; Nakao, Tetsushi; Pournamadri, Ashley; Xiao, Tong; Hajebrahimi, Mohammad Ali; Wasner, Lisa; Stegner, David; Petzold, Tobias; Natarajan, Pradeep; Massberg, Steffen; Tall, Alan R; Schulz, Christian; Wang, Nan.

Blood ; 143(15): 1539-1550, 2024 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-38142422

6.

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.

Bao, Erik L; Nandakumar, Satish K; Liao, Xiaotian; Bick, Alexander G; Karjalainen, Juha; Tabaka, Marcin; Gan, Olga I; Havulinna, Aki S; Kiiskinen, Tuomo T J; Lareau, Caleb A; de Lapuente Portilla, Aitzkoa L; Li, Bo; Emdin, Connor; Codd, Veryan; Nelson, Christopher P; Walker, Christopher J; Churchhouse, Claire; de la Chapelle, Albert; Klein, Daryl E; Nilsson, Björn; Wilson, Peter W F; Cho, Kelly; Pyarajan, Saiju; Gaziano, J Michael; Samani, Nilesh J; Regev, Aviv; Palotie, Aarno; Neale, Benjamin M; Dick, John E; Natarajan, Pradeep; O'Donnell, Christopher J; Daly, Mark J; Milyavsky, Michael; Kathiresan, Sekar; Sankaran, Vijay G.

Nature ; 586(7831): 769-775, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-33057200

7.

Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease.

Rogers, Maximillian A; Bartoli-Leonard, Francesca; Zheng, Kang H; Small, Aeron M; Chen, Hao Yu; Clift, Cassandra L; Asano, Takaharu; Kuraoka, Shiori; Blaser, Mark C; Perez, Katelyn A; Natarajan, Pradeep; Yeang, Calvin; Stroes, Erik S G; Tsimikas, Sotirios; Engert, James C; Thanassoulis, George; O'Donnell, Christopher J; Aikawa, Masanori; Singh, Sasha A; Aikawa, Elena.

Circulation ; 149(5): 391-401, 2024 01 30.

Artículo en Inglés | MEDLINE | ID: mdl-37937463

8.

Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.

Lin, Amy Erica; Bapat, Aneesh C; Xiao, Ling; Niroula, Abhishek; Ye, Jiangchuan; Wong, Waihay J; Agrawal, Mridul; Farady, Christopher J; Boettcher, Andreas; Hergott, Christopher B; McConkey, Marie; Flores-Bringas, Patricio; Shkolnik, Veronica; Bick, Alexander G; Milan, David; Natarajan, Pradeep; Libby, Peter; Ellinor, Patrick T; Ebert, Benjamin L.

Circulation ; 149(18): 1419-1434, 2024 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-38357791

9.

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets.

Vlasschaert, Caitlyn; Mack, Taralynn; Heimlich, J Brett; Niroula, Abhishek; Uddin, Md Mesbah; Weinstock, Joshua; Sharber, Brian; Silver, Alexander J; Xu, Yaomin; Savona, Michael; Gibson, Christopher; Lanktree, Matthew B; Rauh, Michael J; Ebert, Benjamin L; Natarajan, Pradeep; Jaiswal, Siddhartha; Bick, Alexander G.

Blood ; 141(18): 2214-2223, 2023 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-36652671

10.

Age at Menopause, Leukocyte Telomere Length, and Coronary Artery Disease in Postmenopausal Women.

Schuermans, Art; Nakao, Tetsushi; Uddin, Md Mesbah; Hornsby, Whitney; Ganesh, Shriie; Shadyab, Aladdin H; Liu, Simin; Haring, Bernhard; Shufelt, Chrisandra L; Taub, Margaret A; Mathias, Rasika A; Kooperberg, Charles; Reiner, Alexander P; Bick, Alexander G; Manson, JoAnn E; Natarajan, Pradeep; Honigberg, Michael C.

Circ Res ; 133(5): 376-386, 2023 08 18.

Artículo en Inglés | MEDLINE | ID: mdl-37489536

11.

Deep Learning to Estimate Cardiovascular Risk From Chest Radiographs : A Risk Prediction Study.

Weiss, Jakob; Raghu, Vineet K; Paruchuri, Kaavya; Zinzuwadia, Aniket; Natarajan, Pradeep; Aerts, Hugo J W L; Lu, Michael T.

Ann Intern Med ; 177(4): 409-417, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38527287

12.

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program.

Verma, Anurag; Tsao, Noah L; Thomann, Lauren O; Ho, Yuk-Lam; Iyengar, Sudha K; Luoh, Shiuh-Wen; Carr, Rotonya; Crawford, Dana C; Efird, Jimmy T; Huffman, Jennifer E; Hung, Adriana; Ivey, Kerry L; Levin, Michael G; Lynch, Julie; Natarajan, Pradeep; Pyarajan, Saiju; Bick, Alexander G; Costa, Lauren; Genovese, Giulio; Hauger, Richard; Madduri, Ravi; Pathak, Gita A; Polimanti, Renato; Voight, Benjamin; Vujkovic, Marijana; Zekavat, Seyedeh Maryam; Zhao, Hongyu; Ritchie, Marylyn D; Chang, Kyong-Mi; Cho, Kelly; Casas, Juan P; Tsao, Philip S; Gaziano, J Michael; O'Donnell, Christopher; Damrauer, Scott M; Liao, Katherine P.

PLoS Genet ; 18(4): e1010113, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35482673

13.

Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.

Schuermans, Art; Vlasschaert, Caitlyn; Nauffal, Victor; Cho, So Mi Jemma; Uddin, Md Mesbah; Nakao, Tetsushi; Niroula, Abhishek; Klarqvist, Marcus D R; Weeks, Lachelle D; Lin, Amy E; Saadatagah, Seyedmohammad; Lannery, Kim; Wong, Megan; Hornsby, Whitney; Lubitz, Steven A; Ballantyne, Christie; Jaiswal, Siddhartha; Libby, Peter; Ebert, Benjamin L; Bick, Alexander G; Ellinor, Patrick T; Natarajan, Pradeep; Honigberg, Michael C.

Eur Heart J ; 45(10): 791-805, 2024 Mar 07.

Artículo en Inglés | MEDLINE | ID: mdl-37952204

14.

Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program.

Small, Aeron M; Peloso, Gina M; Linefsky, Jason; Aragam, Jayashri; Galloway, Ashley; Tanukonda, Vidisha; Wang, Lu-Chen; Yu, Zhi; Sunitha Selvaraj, Margaret; Farber-Eger, Eric H; Baker, Michael T; Setia-Verma, Shefali; Lee, Simon S K; Preuss, Michael; Ritchie, Marylyn D; Damrauer, Scott M; Rader, Daniel J; Wells, Quinn S; Loos, Ruth; Lubitz, Steven A; Thanassoulis, George; Cho, Kelly; Wilson, Peter W F; Natarajan, Pradeep; O'Donnell, Christopher J.

Circulation ; 147(12): 942-955, 2023 03 21.

Artículo en Inglés | MEDLINE | ID: mdl-36802703

15.

Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.

Portilla-Fernandez, Eliana; Klarin, Derek; Hwang, Shih-Jen; Biggs, Mary L; Bis, Joshua C; Weiss, Stefan; Rospleszcz, Susanne; Natarajan, Pradeep; Hoffmann, Udo; Rogers, Ian S; Truong, Quynh A; Völker, Uwe; Dörr, Marcus; Bülow, Robin; Criqui, Michael H; Allison, Matthew; Ganesh, Santhi K; Yao, Jie; Waldenberger, Melanie; Bamberg, Fabian; Rice, Kenneth M; Essers, Jeroen; Kapteijn, Daniek M C; van der Laan, Sander W; de Knegt, Rob J; Ghanbari, Mohsen; Felix, Janine F; Ikram, M Arfan; Kavousi, Maryam; Uitterlinden, Andre G; Roks, Anton J M; Danser, A H Jan; Tsao, Philip S; Damrauer, Scott M; Guo, Xiuqing; Rotter, Jerome I; Psaty, Bruce M; Kathiresan, Sekar; Völzke, Henry; Peters, Annette; Johnson, Craig; Strauch, Konstantin; Meitinger, Thomas; O'Donnell, Christopher J; Dehghan, Abbas.

Hum Mol Genet ; 31(20): 3566-3579, 2022 10 10.

Artículo en Inglés | MEDLINE | ID: mdl-35234888

16.

TET2-mutant clonal hematopoiesis and risk of gout.

Agrawal, Mridul; Niroula, Abhishek; Cunin, Pierre; McConkey, Marie; Shkolnik, Veronica; Kim, Peter G; Wong, Waihay J; Weeks, Lachelle D; Lin, Amy E; Miller, Peter G; Gibson, Christopher J; Sekar, Aswin; Schaefer, Inga-Marie; Neuberg, Donna; Stone, Richard M; Bick, Alexander G; Uddin, Md Mesbah; Griffin, Gabriel K; Jaiswal, Siddhartha; Natarajan, Pradeep; Nigrovic, Peter A; Rao, Deepak A; Ebert, Benjamin L.

Blood ; 140(10): 1094-1103, 2022 09 08.

Artículo en Inglés | MEDLINE | ID: mdl-35714308

17.

Association of clonal hematopoiesis with chronic obstructive pulmonary disease.

Miller, Peter G; Qiao, Dandi; Rojas-Quintero, Joselyn; Honigberg, Michael C; Sperling, Adam S; Gibson, Christopher J; Bick, Alexander G; Niroula, Abhishek; McConkey, Marie E; Sandoval, Brittany; Miller, Brian C; Shi, Weiwei; Viswanathan, Kaushik; Leventhal, Matthew; Werner, Lillian; Moll, Matthew; Cade, Brian E; Barr, R Graham; Correa, Adolfo; Cupples, L Adrienne; Gharib, Sina A; Jain, Deepti; Gogarten, Stephanie M; Lange, Leslie A; London, Stephanie J; Manichaikul, Ani; O'Connor, George T; Oelsner, Elizabeth C; Redline, Susan; Rich, Stephen S; Rotter, Jerome I; Ramachandran, Vasan; Yu, Bing; Sholl, Lynette; Neuberg, Donna; Jaiswal, Siddhartha; Levy, Bruce D; Owen, Caroline A; Natarajan, Pradeep; Silverman, Edwin K; van Galen, Peter; Tesfaigzi, Yohannes; Cho, Michael H; Ebert, Benjamin L.

Blood ; 139(3): 357-368, 2022 01 20.

Artículo en Inglés | MEDLINE | ID: mdl-34855941

18.

Diastolic Blood Pressure Alleles Improve Congenital Heart Defect Repair Outcomes.

Breeyear, Joseph H; Keaton, Jacob M; Torstenson, Eric S; Smith, Andrew H; Klarin, Derek; Damrauer, Scott M; Natarajan, Pradeep; Van Driest, Sara L; Weiner, Jeffrey G; Kannankeril, Prince J; Edwards, Todd L.

Circ Res ; 130(7): 1030-1037, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35199555

19.

Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease.

Natarajan, Pradeep.

Arterioscler Thromb Vasc Biol ; 43(1): 3-14, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36353993

20.

Author Correction: Clonal haematopoiesis and risk of chronic liver disease.

Wong, Waihay J; Emdin, Connor; Bick, Alexander G; Zekavat, Seyedeh M; Niroula, Abhishek; Pirruccello, James P; Dichtel, Laura; Griffin, Gabriel; Uddin, Md Mesbah; Gibson, Christopher J; Kovalcik, Veronica; Lin, Amy E; McConkey, Marie E; Vromman, Amelie; Sellar, Rob S; Kim, Peter G; Agrawal, Mridul; Weinstock, Joshua; Long, Michelle T; Yu, Bing; Banerjee, Rajarshi; Nicholls, Rowan C; Dennis, Andrea; Kelly, Matt; Loh, Po-Ru; McCarroll, Steve; Boerwinkle, Eric; Vasan, Ramachandran S; Jaiswal, Siddhartha; Johnson, Andrew D; Chung, Raymond T; Corey, Kathleen; Levy, Daniel; Ballantyne, Christie; Ebert, Benjamin L; Natarajan, Pradeep.

Nature ; 619(7970): E47, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37400552

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